Antidepressivos, ansiolíticos, hipnóticos e sedativos : uma análise dos gastos em Minas Gerais

Barbi, Lucas and Carvalho, Liliany Mara Silva and Luz, Tatiana Chama Borges (2019) Antidepressivos, ansiolíticos, hipnóticos e sedativos : uma análise dos gastos em Minas Gerais. Physis : Revista de Saúde Coletiva, 29 (4). e290407. ISSN 1809-4481 (

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The allocation of financial resources on medicines procurement is one of the greatest challenges to the effectiveness of the Pharmaceutical Services in the Brazilian National Health System. However, there are few studies evaluating this expenditure trends at state level, especially with antidepressants, anxiolytics, hypnotics and sedatives. The study evaluated public expenditure trends and drivers for these therapeutic classes in Minas Gerais state, Brazil, by using data from SIAD database [Sistema Integrado de Administração de Materiais e Serviços] from 2010 to 2015. Total expenditure, volume and also expenditures with medicines not included in the essential lists were estimated. The top 10 medicines in terms of expenditure and drugs accounting for 90% of the total cost were identified. Decomposition analysis was conducted to assess the drivers of expenditure. Expenditure in the period totaled R$ 81 million and increased 2.5 times from 2010 to 2015. Antidepressants accounted for 89% of expenses and 71% of volume. Price contributed positively to the expenditure variation during the period, especially in antidepressants. The results highlight the need of improvement of public procurement procedures adopted by Minas Gerais state.