Uterine fibroid embolization for symptomatic fibroids : study at a teaching hospital in Kenya

Mutai, John Kiprop and Vinayak, Sudhir and Stones, William and Hacking, Nigel and Mariara, Charles (2015) Uterine fibroid embolization for symptomatic fibroids : study at a teaching hospital in Kenya. Journal of Clinical Imaging Science, 5. (https://doi.org/10.4103/2156-7514.154351)

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Abstract

OBJECTIVE: Characterization of magnetic (MRI) features in women undergoing uterine fibroid embolization (UFE) and identification of clinical correlates in an African population. MATERIALS AND METHODS: Patients with symptomatic fibroids who are selected to undergo UFE at the hospital formed the study population. The baseline MRI features, baseline symptom score, short-term imaging outcome, and mid-term symptom scores were analyzed for interval changes. Assessment of potential associations between short-term imaging features and mid-term symptom scores was also done. RESULTS: UFE resulted in statistically significant reduction (P < 0.001) of dominant fibroid, uterine volumes, and reduction of symptom severity scores, which were 43.7%, 40.1%, and 37.8%, respectively. Also, 59% of respondents had more than 10 fibroids. The predominant location of the dominant fibroid was intramural. No statistically significant association was found between clinical and radiological outcome. CONCLUSION: The response of uterine fibroids to embolization in the African population is not different from the findings reported in other studies from the west. The presence of multiple and large fibroids in this study is consistent with the case mix described in other studies of African-American populations. Patient counseling should emphasize the independence of volume reduction and symptom improvement. Though volume changes are of relevance for the radiologist in understanding the evolution of the condition and identifying potential technical treatment failures, it should not be the main basis of evaluation of treatment success.

ORCID iDs

Mutai, John Kiprop, Vinayak, Sudhir, Stones, William ORCID logoORCID: https://orcid.org/0000-0003-0699-2381, Hacking, Nigel and Mariara, Charles;
  • Item type:Article
    ID code:71600
    Dates:
    Date
    Event
    31 March 2015
    Published
    24 February 2015
    Accepted
    Notes:This study was funded by the Aga Khan University
    Subjects:Medicine
    Department:Faculty of Engineering > Civil and Environmental Engineering
    Depositing user: Pure Administrator
    Date deposited:27 Feb 2020 16:25
    Last modified:11 Nov 2024 12:36
    URI:https://strathprints.strath.ac.uk/id/eprint/71600
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