Doppler colour flow imaging and flow quantification with a novel forward-viewing intravascular ultrasound system

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Gatzoulis, L. and Ramnarine, K. and Pye, S. and Anderson, T. and Newby, D. and Hoskins, P. and McDicken, N. (2003) Doppler colour flow imaging and flow quantification with a novel forward-viewing intravascular ultrasound system. Ultrasound in Medicine and Biology, 29 (1). pp. 53-64. ISSN 0301-5629 (http://dx.doi.org/10.1016/S0301-5629(02)00699-3)

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Abstract

The aim of this work was to investigate the potential of a novel forward-viewing intravascular ultrasound (IVUS) system for flow quantification and colour flow imaging combined with B-mode imaging. A stiff 3.8-mm diameter catheter was used to scan a 72° sector ahead of its tip. Operating at 30 MHz, the catheter was integrated with an IVUS scanner and a radiofrequency (RF) data-acquisition system. RF data were software processed for producing B-mode images and deriving velocity estimates. Steady flow in the range of 45 to 146 mL/min toward the catheter, was used in wall-less tissue-mimicking phantoms simulating healthy lumen (8-mm diameter), 30% diameter symmetrical stenosis and 37% diameter eccentric stenosis. The system provided colour flow images and good estimation of peak velocity and volumetric flows (within 1% to 9% and 16% to 48%, respectively, of calculated values) at 5 to 7 mm distal to the catheter. A sector forward-viewing IVUS imaging/Doppler system is suitable for combined anatomical and functional assessment of stenosed vessels.

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