Administration of a long-acting antipsychotic injection to a child while managing contraindicated polypharmacy interactions and transition between services

Akram, Gazala and Mitchell, Fiona (2019) Administration of a long-acting antipsychotic injection to a child while managing contraindicated polypharmacy interactions and transition between services. BMJ Case Reports, 12 (6). e228509. ISSN 1757-790X (https://doi.org/10.1136/bcr-2018-228509)

[thumbnail of Akram-Mitchell-BMJCR-2019-Administration-of-a-long-acting-antipsychotic-injection-to-a-child-while-managing]
Preview
Text. Filename: Akram_Mitchell_BMJCR_2019_Administration_of_a_long_acting_antipsychotic_injection_to_a_child_while_managing.pdf
Accepted Author Manuscript

Download (641kB)| Preview

Abstract

Second-generation antipsychotics are used to treat a variety of psychiatric symptoms and illnesses as well as the behavioural aspects of various neurodevelopmental disorders. However, there is reluctance in using second-generation long-acting injectable antipsychotics in child psychiatry services. We present a case of a 12-year-old child whose presentation and medication regime warranted the use of aripiprazole long-acting injection against a backdrop of potential CYP P450 enzyme interactions as a consequence of polypharmacy. The case also describes the difficulties encountered working across different health sectors and agencies and highlights the ongoing need for skills-based Continuous Professional Development for Child and Adolescent Mental Health Services-based nursing staff.

ORCID iDs

Akram, Gazala ORCID logoORCID: https://orcid.org/0000-0003-3207-8091 and Mitchell, Fiona;