Picture of boy being examining by doctor at a tuberculosis sanatorium

Understanding our future through Open Access research about our past...

Strathprints makes available scholarly Open Access content by researchers in the Centre for the Social History of Health & Healthcare (CSHHH), based within the School of Humanities, and considered Scotland's leading centre for the history of health and medicine.

Research at CSHHH explores the modern world since 1800 in locations as diverse as the UK, Asia, Africa, North America, and Europe. Areas of specialism include contraception and sexuality; family health and medical services; occupational health and medicine; disability; the history of psychiatry; conflict and warfare; and, drugs, pharmaceuticals and intoxicants.

Explore the Open Access research of the Centre for the Social History of Health and Healthcare. Or explore all of Strathclyde's Open Access research...

Image: Heart of England NHS Foundation Trust. Wellcome Collection - CC-BY.

NMR spectroscopy methods in metabolic phenotyping

Parkinson, John A. (2018) NMR spectroscopy methods in metabolic phenotyping. In: The Handbook of Metabolic Phenotyping. Elsevier, Cambridge, MA, pp. 53-96. ISBN 9780128122945

Full text not available in this repository. Request a copy from the Strathclyde author


NMR spectroscopy is an established, versatile, widely applicable analytical technique forming one of the cornerstone methods for metabolic profiling, metabonomics, metabolomics, and metabolic phenotyping applied to complex biofluid and tissue samples. From sample storage and preparation conditions through basic one-dimensional proton and two-dimensional proton only and proton-carbon correlated NMR techniques, this chapter moves on to consider the quest for ever more advanced NMR methods to improve data resolution, increase analyte detection limits, and robustly quantify components within complex biofluid and tissue matrices. The work is a guide to the established state-of-the-art in bioanalytical NMR methods, and through its course addresses some pitfalls to be aware of as well as providing a window through which the future potential shape of the field may be considered.