Picture of sea vessel plough through rough maritime conditions

Innovations in marine technology, pioneered through Open Access research...

Strathprints makes available scholarly Open Access content by researchers in the Department of Naval Architecture, Ocean & Marine Engineering based within the Faculty of Engineering.

Research here explores the potential of marine renewables, such as offshore wind, current and wave energy devices to promote the delivery of diverse energy sources. Expertise in offshore hydrodynamics in offshore structures also informs innovations within the oil and gas industries. But as a world-leading centre of marine technology, the Department is recognised as the leading authority in all areas related to maritime safety, such as resilience engineering, collision avoidance and risk-based ship design. Techniques to support sustainability vessel life cycle management is a key research focus.

Explore the Open Access research of the Department of Naval Architecture, Ocean & Marine Engineering. Or explore all of Strathclyde's Open Access research...

A numerical approach for the assessment of obesity-induced vascular changes in children

Kazakidi, Asimina (2018) A numerical approach for the assessment of obesity-induced vascular changes in children. In: 8th World Congress of Biomechanics, 2018-07-08 - 2018-07-12, Convention Centre Dublin. (In Press)

Text (Kazakidi-WCB2018-A-numerical-approach-for-the-assessment-of-obesity-induced)
Accepted Author Manuscript

Download (88kB) | Preview


Obesity in children and adolescents has taken epidemic proportions in recent years and has become one of the major challenges of the 21st century. Primarily a dietary disease, obesity is believed to accelerate the initiation and progression of endothelial dysfunction [1], one of the early biological markers for atherosclerotic lesions that underlie most cardiovascular diseases. Several markers have been proposed to help the clinical assessment of endothelial damage in high-risk paediatric patients. In obese children, arterial changes can painlessly be evaluated with measurements of the aortic and carotid intima-media thickness (IMT) and flowmediated dilatation (FMD) of the brachial, radial and femoral arteries [2]. Pulse wave analysis is additionally utilised to assess arterial stiffness, distensibility and compliance. This study observes childhood obesity under the magnifying lens of blood flow mechanics associated with obesity-induced vascular changes. The scope is to develop a safe and high-fidelity multi-scale computational tool for prognostic markers and predictive personalised care of obesity-related cardiovascular diseases, and transfer it into the paediatric reality. The current presentation will discuss a computational model of an arterial conduit during FDM.