Blood flow simulations in models of the pulmonary bifurcation to facilitate treatment of adults with congenital heart disease

Boumpouli, M. and Danton, M. and Gourlay, T. and Kazakidi, A. (2018) Blood flow simulations in models of the pulmonary bifurcation to facilitate treatment of adults with congenital heart disease. In: 31st Scottish Fluid Mechanics Meeting 2018, 2018-05-29 - 2018-05-29, University of Aberdeen.

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    Abstract

    Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease, for which patients require surgical intervention at a very young age. Although these patients have long survival rates, they are at risk of chronic complications and frequently require re-operations with the most common being pulmonary valve replacement (PVR). However, the decision for surgical intervention is currently based on clinical indications and the right timing for PVR remains ambiguous [1,2]. The overall objective of this work is to identify a computational metric that will help assess the right timing for surgical intervention in adults with repaired tetralogy of Fallot. This current study concerns a preliminary computational analysis of blood flow in simplified geometries of the pulmonary bifurcation. The focus lies on the effect of geometric and haemodynamic parameters on the wall shear stress patterns around the pulmonary bifurcation.