Estimating fluorescence lifetimes using the expectation-maximisation algorithm

Gao, Kai and Li, David Day-Uei (2018) Estimating fluorescence lifetimes using the expectation-maximisation algorithm. Electronics Letters, 54 (1). pp. 1-2. ISSN 0013-5194

[img]
Preview
 Text (Gao-Li-EL2017-Estimating-fluorescence-lifetimes-using-the-expectation)
Gao_Li_EL2017_Estimating_fluorescence_lifetimes_using_the_expectation.pdf
Accepted Author Manuscript
Download (260kB)| Preview

    Abstract

    The expectation-maximisation (EM) algorithm uses incomplete data to get the estimation of the probabilistic model parameter, and it has been widely used in machine learning. EM techniques are applied to estimate fluorescence lifetimes in time-correlated single-photon counting based fluorescence lifetime imaging experiments without measuring the instrument response functions. The results of Monte Carlo simulations indicate that the proposed approach can obtain better or comparable accuracy and precision performances than the previously reported method.

    Author(s):Gao, Kai and Li, David Day-Uei ORCID logoORCID: https://orcid.org/0000-0002-6401-4263
    Item type:Article
    ID code:64064
    Notes:This paper is a postprint of a paper submitted to and accepted for publication in Electronics Letters and is subject to Institution of Engineering and Technology Copyright. The copy of record is available at IET Digital Library.
    Keywords:fluorescence, expectation-maximization algorithm, Monte Carlo simulations, Electrical engineering. Electronics Nuclear engineering, Electrical and Electronic Engineering
    Subjects:Technology > Electrical engineering. Electronics Nuclear engineering
    Department:Strategic Research Themes > Health and Wellbeing
    Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
    Depositing user: Pure Administrator
    Date deposited:16 May 2018 12:58
    Last modified:25 Jan 2020 07:32
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/64064
    Export data:
    CORE (COnnecting REpositories)