A novel Hemi-Body Irradiation technique using electron beams (HBIe−)

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Delinikolas, Panagiotis and Patatoukas, Georgios and Kouloulias, Vassilios and Dilvoi, Maria and Plousi, Agapi and Efstathopoulos, Efstathios and Platoni, Kalliopi (2018) A novel Hemi-Body Irradiation technique using electron beams (HBIe−). Physica Medica, 46. pp. 16-24. ISSN 1120-1797 (https://doi.org/10.1016/j.ejmp.2017.12.022)

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Abstract

Purpose Certain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe−) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques. Materials and methods The HBIe− technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup. The patient is positioned in 'Stanford' technique positions. The geometrical setup provides both optimal dose homogeneity and dose deposition up to a depth of 2 cm. To confirm this, the following characteristics were measured and evaluated: a) percentage depth dose (PDD) on the treatment plane produced by a single electron beam at perpendicular incidence for six fields at 'Stanford' angles, b) 2D profile of the entrance dose on the treatment plane produced by a single field and c) the total surface dose on an anthropomorphic phantom delivered by all 6 fields. Results The resulting homogeneity of the surface dose in the treatment plane for an average patient was 5–6%, while surface dose homogeneity on the anthropomorphic phantom was 7% for both the upper and the lower HBIe− variants. The total PDD exhibits an almost linear decrease to a practical range of 2 g/cm2. Conclusion In conclusion, HBIe− was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin.

ORCID iDs

Delinikolas, Panagiotis ORCID logoORCID: https://orcid.org/0000-0003-1409-8486, Patatoukas, Georgios, Kouloulias, Vassilios, Dilvoi, Maria, Plousi, Agapi, Efstathopoulos, Efstathios and Platoni, Kalliopi;
  • Item type:Article
    ID code:63436
    Dates:
    Date
    Event
    28 February 2018
    Published
    27 December 2017
    Accepted
    Subjects:Science > Physics
    Department:Faculty of Science > Physics
    Depositing user: Pure Administrator
    Date deposited:07 Mar 2018 12:49
    Last modified:11 Nov 2024 11:56
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/63436
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