Delivering natural products and biotherapeutics to improve drug efficacy

Obeid, Mohammad A. and Al Qaraghuli, Mohammed M. and Alsaadi, Manal and Alzahrani, Abdullah R. and Niwasabutra, Kanidta and Ferro, Valerie A. (2017) Delivering natural products and biotherapeutics to improve drug efficacy. Therapeutic Delivery, 8 (11). 947–956. ISSN 2041-5990

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    Abstract

    Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery processes and the subsequent lack of investment from the pharmaceutical industry, are associated with these areas. New techniques are producing compounds with appropriate activity at a faster rate. While the formulation of these combined with drug-delivery systems offers a promising approach for expanding the drug developments available to modern medicine. Here, various classes of drug-delivery systems are described and the advantages they bring to small molecule and biotherapeutic targeting are highlighted. This is an attractive approach to the pharmaceutical industry and the rising trend in research in this area is examined in brief.

    Author(s):Obeid, Mohammad A. ORCID logoORCID: https://orcid.org/0000-0003-0244-8370, Al Qaraghuli, Mohammed M. ORCID logoORCID: https://orcid.org/0000-0003-1823-6671, Alsaadi, Manal, Alzahrani, Abdullah R. ORCID logoORCID: https://orcid.org/0000-0001-7782-0574, Niwasabutra, Kanidta ORCID logoORCID: https://orcid.org/0000-0001-7543-3191 and Ferro, Valerie A. ORCID logoORCID: https://orcid.org/0000-0003-1967-3603
    Item type:Article
    ID code:61740
    Keywords:drug research, traditional medicine, drug discovery, biotherapeutics, drug delivery systems, natural products, Therapeutics. Pharmacology, Drug Discovery
    Subjects:Medicine > Therapeutics. Pharmacology
    Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
    Depositing user: Pure Administrator
    Date deposited:06 Sep 2017 14:04
    Last modified:02 Aug 2019 02:54
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/61740
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