Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

Rucinskaite, Gabriele and Thompson, Sebastian A. and Paterson, Sureyya and De La Rica, Roberto (2017) Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose. Nanoscale, 9 (17). pp. 5404-5407. ISSN 2040-3372

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    Abstract

    A method is proposed for controlling the number of nanoparticles bound to cell membranes via RGDS peptide-integrin interactions. It consists of propelling nanoparticles bearing the peptides with enzymes (glucose oxidase), which disrupts biomolecular interactions as a function of the concentration of enzyme substrate (glucose).

    Author(s):Rucinskaite, Gabriele, Thompson, Sebastian A., Paterson, Sureyya and De La Rica, Roberto
    Item type:Article
    ID code:61643
    Keywords:nanoparticles, cell membranes, peptides, Chemistry, Materials Science(all)
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:28 Aug 2017 11:10
    Last modified:19 Jun 2019 12:35
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/61643
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