Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

Rucinskaite, Gabriele and Thompson, Sebastian A. and Paterson, Sureyya and De La Rica, Roberto (2017) Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose. Nanoscale, 9 (17). pp. 5404-5407. ISSN 2040-3372 (https://doi.org/10.1039/c7nr00298j)

[thumbnail of Rucinskaite-etal-Nanoscale2017-Enzyme-coated-Janus-nanoparticles-that-selectively-bind-cell-receptors]
Preview
 Text. Filename: Rucinskaite_etal_Nanoscale2017_Enzyme_coated_Janus_nanoparticles_that_selectively_bind_cell_receptors.pdf
Final Published Version
License: Creative Commons Attribution 3.0 logo
Download (818kB)| Preview

Abstract

A method is proposed for controlling the number of nanoparticles bound to cell membranes via RGDS peptide-integrin interactions. It consists of propelling nanoparticles bearing the peptides with enzymes (glucose oxidase), which disrupts biomolecular interactions as a function of the concentration of enzyme substrate (glucose).

ORCID iDs

Rucinskaite, Gabriele, Thompson, Sebastian A., Paterson, Sureyya ORCID logoORCID: https://orcid.org/0000-0001-5433-7811 and De La Rica, Roberto;
  • Item type:Article
    ID code:61643
    Dates:
    Date
    Event
    7 May 2017
    Published
    12 April 2017
    Published Online
    11 April 2017
    Accepted
    Keywords:nanoparticles, cell membranes, peptides, Chemistry, Materials Science(all)
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:28 Aug 2017 11:10
    Last modified:12 Feb 2022 01:23
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/61643
CORE (COnnecting REpositories)