Can parasitic worms cure the modern world's ills?
Harnett, Margaret M. and Harnett, William (2017) Can parasitic worms cure the modern world's ills? Trends in Parasitology. ISSN 1471-4922
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Abstract
There has been increasing recognition that the alarming surge in allergy and autoimmunity in the industrialised and developing worlds shadows the rapid eradication of pathogens, such as parasitic helminths. Appreciation of this has fuelled an explosion in research investigating the therapeutic potential of these worms. This review considers the current state-of-play with a particular focus on exciting recent advances in the identification of potential novel targets for immunomodulation that can be exploited therapeutically. Furthermore, we contemplate the prospects for designing worm-derived immunotherapies for an ever-widening range of inflammatory diseases, including, for example, obesity, cardiovascular disease, and ageing as well as neurodevelopmental disorders like autism.
Author(s): | Harnett, Margaret M. and Harnett, William ![]() | Item type: | Article |
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ID code: | 61472 |
Keywords: | helminth, drug development, immunomodulation, Microbiology, Infectious Diseases, Parasitology |
Subjects: | Science > Microbiology |
Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
Depositing user: | Pure Administrator |
Date deposited: | 03 Aug 2017 15:41 |
Last modified: | 15 Nov 2019 05:57 |
Related URLs: | |
URI: | https://strathprints.strath.ac.uk/id/eprint/61472 |
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