Establishing and prioritizing research questions for the treatment of alopecia areata : the Alopecia Areata Priority Setting Partnership

Macbeth, A.E. and Tomlinson, J. and Messenger, A.G. and Moore-Millar, K. and Michaelides, C. and Shipman, A.R. and Kassim, J.M. and Brockley, J.R. and Szczecinska, W. and Farrant, P. and Robinson, R. and Rodgers, J. and Chambers, J. and Upadhyaya, S. and Harries, M.J. (2017) Establishing and prioritizing research questions for the treatment of alopecia areata : the Alopecia Areata Priority Setting Partnership. The British journal of dermatology, 176 (5). pp. 1316-1320. ISSN 1365-2133 (https://doi.org/10.1111/bjd.15099)

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Abstract

Background: Alopecia areata (AA) is a common hair loss disorder that results in patchy to complete hair loss. Many uncertainties exist around the most effective treatments for this condition. Objectives: To identify uncertainties in AA management and treatment that are important to both service users (people with hair loss, carers and relatives) and healthcare professionals. Methods: An AA priority setting partnership was established between patients, their carers and relatives, and healthcare professionals to identify the most important uncertainties in AA. The methodology of the James Lind Alliance was followed to ensure a balanced, inclusive and transparent process. Results:In total, 2747 treatment uncertainties were submitted by 912 participants, of which 1012 uncertainties relating to AA (and variants) were analysed. Questions were combined into ‘indicative uncertainties’ following a structured format. A series of ranking exercises further reduced this list to a top 25 that were taken to a final prioritization workshop where the top 10 priorities were agreed. Conclusions: We present the top 10 research priorities for AA to guide researchers and funding bodies to support studies important to both patients and clinicians.

  • Item type:Article
    ID code:60934
    Dates:
    Date
    Event
    31 May 2017
    Published
    16 April 2017
    Published Online
    23 September 2016
    Accepted
    Notes:This is the peer reviewed version of the following article: Macbeth, A. E., Tomlinson, J., Messenger, A. G., Moore-Millar, K., Michaelides, C., Shipman, A. R., ... Harries, M. J. (2017). Establishing and prioritizing research questions for the treatment of alopecia areata: the Alopecia Areata Priority Setting Partnership. The British journal of dermatology, 176(5), 1316-1320. DOI: 10.1111/bjd.15099, which has been published in final form at http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjd.15099/abstract. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
    Subjects:Medicine > Dermatology
    Department:Faculty of Engineering > Design, Manufacture and Engineering Management
    Depositing user: Pure Administrator
    Date deposited:14 Jun 2017 10:39
    Last modified:11 Nov 2024 11:42
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/60934
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