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EPRC is a leading institute in Europe for comparative research on public policy, with a particular focus on regional development policies. Spanning 30 European countries, EPRC research programmes have a strong emphasis on applied research and knowledge exchange, including the provision of policy advice to EU institutions and national and sub-national government authorities throughout Europe.

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Longitudinal study of the associations between change in sedentary behavior and change in adiposity during childhood and adolescence : Gateshead Millennium study

Mann, K D and Howe, L D and Basterfield, L and Parkinson, K N and Pearce, M S and Reilly, J K and Adamson, A J and Reilly, J J and Janssen, X (2017) Longitudinal study of the associations between change in sedentary behavior and change in adiposity during childhood and adolescence : Gateshead Millennium study. International Journal of Obesity. ISSN 0307-0565

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BACKGROUND: Sedentary time (ST) has been reported to have a range of negative health effects in adults, however, the evidence for such effects among children and adolescents is sparse. The primary aim of the study was to examine associations between changes in sedentary behavior (time and fragmentation) and changes in adiposity across childhood and adolescence. METHODS: Participants were recruited as part of the Gateshead Millennium Study. Measures were taken at age 7y (n=502), 9y (n=506), 12y (n=420) and 15y (n=306). Participants wore an ActiGraph GT1M and accelerometer epochs were 'sedentary' when recorded counts were ⩽25 counts/15 s. ST was calculated and fragmentation (SF) was assessed by calculating the number of sedentary bouts per sedentary hour. Associations of changes in ST and SF with changes in adiposity (Body Mass Index (BMI), and Fat Mass Index (FMI)) were examined using bivariate linear spline models. RESULTS: Increasing ST by 1% per year was associated with an increase in BMI of 0.08 kg/m(2)/year (95%CI: 0.06-0.10; P<0.001) and FMI of 0.15 kg/m(2)/year (0.11-0.19; P<0.001). Change in SF was associated with BMI and FMI (P<0.001). An increase of 1 bout per sedentary hour per year (i.e. sedentary time becoming more fragmented) was associated with an increase in BMI of 0.07 kg/m(2)/year (0.06-0.09; P<0.001) and an increase in FMI of 0.14 kg/m(2)/year (0.10-0.18; P<0.001) over the 8y period. However, an increase in SF between 9y-12y was associated with a 0.09 kg/m(2)/year decrease in BMI (-0.18-0.00; p=0.046) and 0.11 kg/m(2)/year decrease in FMI (-0.22-0.00; P=0.049). CONCLUSIONS: Increased ST and increased SF from 7y to 15y were associated with increased adiposity. This is the first study to show age-specific associations between change in objectively measured sedentary behaviour and adiposity after adjustment of MVPA in children and adolescents.. The study suggests that, targeting sedentary behaviour for obesity prevention may be most effective during periods in which we see large increases in ST.International Journal of Obesity accepted article preview online, 15 March 2017. doi:10.1038/ijo.2017.69.