Comment on 'A novel method for fast and robust estimation of fluorescence decay dynamics using constrained least-square deconvolution with Laguerre expansion'

Zhang, Yongliang and Li, David Day-Uei (2017) Comment on 'A novel method for fast and robust estimation of fluorescence decay dynamics using constrained least-square deconvolution with Laguerre expansion'. Physics in Medicine and Biology, 62 (4). pp. 1632-1636. ISSN 0031-9155

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    Abstract

    This comment is to clarify that Poisson noise instead of Gaussian noise shall be included to assess the performances of least-squares deconvolution with Laguerre expansion (LSD-LE) for analysing fluorescence lifetime imaging (FLIM) data obtained from time-resolved systems. Moreover, we also corrected an equation in the paper. As the LSD-LE approach is rapid and has potential to be widely applied not only for diagnostic but for wider bioimaging applications, it is desirable to have precise noise models and equations.

    Author(s):Zhang, Yongliang and Li, David Day-Uei
    Item type:Article
    ID code:56725
    Keywords:Poisson noise, Gaussian noise, least-squares deconvolution, Laguerre expansion, fluorescence lifetime imaging, bioimaging, noise models, Optics. Light, Atomic and Molecular Physics, and Optics, Biotechnology
    Subjects:Science > Physics > Optics. Light
    Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
    Strategic Research Themes > Health and Wellbeing
    Depositing user: Pure Administrator
    Date deposited:23 Jun 2016 08:32
    Last modified:05 Jun 2019 02:41
    URI:https://strathprints.strath.ac.uk/id/eprint/56725
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