Comment on 'A novel method for fast and robust estimation of fluorescence decay dynamics using constrained least-square deconvolution with Laguerre expansion'
Zhang, Yongliang and Li, David Day-Uei (2017) Comment on 'A novel method for fast and robust estimation of fluorescence decay dynamics using constrained least-square deconvolution with Laguerre expansion'. Physics in Medicine and Biology, 62 (4). pp. 1632-1636. ISSN 0031-9155
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Text (Zhang-Li-PMB2016-Gaussian-or-poisson-noise)
Zhang_Li_PMB2016_Gaussian_or_poisson_noise.pdf Accepted Author Manuscript Download (1MB)| Preview |
Abstract
This comment is to clarify that Poisson noise instead of Gaussian noise shall be included to assess the performances of least-squares deconvolution with Laguerre expansion (LSD-LE) for analysing fluorescence lifetime imaging (FLIM) data obtained from time-resolved systems. Moreover, we also corrected an equation in the paper. As the LSD-LE approach is rapid and has potential to be widely applied not only for diagnostic but for wider bioimaging applications, it is desirable to have precise noise models and equations.
Author(s): | Zhang, Yongliang and Li, David Day-Uei | Item type: | Article |
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ID code: | 56725 |
Keywords: | Poisson noise, Gaussian noise, least-squares deconvolution, Laguerre expansion, fluorescence lifetime imaging, bioimaging, noise models, Optics. Light, Atomic and Molecular Physics, and Optics, Biotechnology |
Subjects: | Science > Physics > Optics. Light |
Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Strategic Research Themes > Health and Wellbeing |
Depositing user: | Pure Administrator |
Date deposited: | 23 Jun 2016 08:32 |
Last modified: | 05 Jun 2019 02:41 |
URI: | https://strathprints.strath.ac.uk/id/eprint/56725 |
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