Fast bi-exponential fluorescence lifetime imaging analysis methods

Li, David Day-Uei and Yu, Hongqi and Chen, Yu (2015) Fast bi-exponential fluorescence lifetime imaging analysis methods. Optics Letters, 40 (3). pp. 336-339. ISSN 0146-9592 (https://doi.org/10.1364/OL.40.000336)

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Abstract

A new hardware-friendly bi-exponential fluorescence lifetime imaging (FLIM) algorithm has been proposed. Compared to conventional FLIM software, the proposed algorithms are non-iterative offering direct calculation of lifetimes and therefore suitable for real-time applications. They can be applicable to single-channel or 2D multi-channel time-correlated single-photon counting (TCSPC) systems. The proposed methods have been tested on both synthesized and realistic FLIM data, and we have compared their performances with other recently proposed non-fitting bi-exponential techniques showing promising applications in future massive solid-state TCSPC imagers.

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  Item type:	Article
  ID code:	51183
  Dates:	Date Event 1 February 2015 Published 21 January 2015 Published Online 1 December 2014 Accepted
  Notes:	© 2014 Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modifications of the content of this paper are prohibited.
  Subjects:	Science > Physics > Optics. Light
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Faculty of Science > Physics Technology and Innovation Centre > Bionanotechnology
  Depositing user:	Pure Administrator
  Date deposited:	03 Feb 2015 10:23
  Last modified:	17 Apr 2024 00:20
  Related URLs:	Journal or Publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/51183