Fluorescence lifetime extraction algorithm based on multiple signal classification

Yu, Hongqi and Li, David Day Uei (2015) Fluorescence lifetime extraction algorithm based on multiple signal classification. Electronics Letters, 51 (1). pp. 81-83. ISSN 0013-5194 (https://doi.org/10.1049/el.2014.3382)

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Abstract

The multiple signal classification algorithm has been widely used in array signal processing for direction-of-arrival estimation. In this reported work, this algorithm has been applied, for the first time to our knowledge, to estimate fluorescence lifetimes for fluorescence lifetime imaging microscopy. Monte Carlo simulations were carried out to test its performance compared with the previously reported integral equation method, the centre-of-mass method and the phasor method. Simulation results show that the multiple signal classification algorithm can achieve comparable or better results than the others. More importantly, it can easily resolve multi-exponential decays.

ORCID iDs

Li, David Day Uei ORCID: https://orcid.org/0000-0002-6401-4263

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• Item metadata

  Item type:	Article
  ID code:	51044
  Dates:	Date Event 8 January 2015 Published 19 December 2014 Published Online 2 December 2014 Accepted
  Notes:	This paper is a postprint of a paper submitted to and accepted for publication in Electronics Letters and is subject to Institution of Engineering and Technology Copyright. The copy of record is available at IET Digital Library
  Subjects:	Technology > Electrical engineering. Electronics Nuclear engineering
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences University of Strathclyde > University of Strathclyde
  Depositing user:	Pure Administrator
  Date deposited:	13 Jan 2015 15:50
  Last modified:	11 Nov 2024 10:55
  Related URLs:	Scopus publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/51044