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Driving innovations in manufacturing: Open Access research from DMEM

Strathprints makes available Open Access scholarly outputs by Strathclyde's Department of Design, Manufacture & Engineering Management (DMEM).

Centred on the vision of 'Delivering Total Engineering', DMEM is a centre for excellence in the processes, systems and technologies needed to support and enable engineering from concept to remanufacture. From user-centred design to sustainable design, from manufacturing operations to remanufacturing, from advanced materials research to systems engineering.

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A comparative study of secondary ion yield from model biological membranes using Aun + and C60 + primary ion sources

Baker, M. J. and Fletcher, J. S. and Jungnickel, H. and Lockyer, N. P. and Vickerman, J. C. (2006) A comparative study of secondary ion yield from model biological membranes using Aun + and C60 + primary ion sources. Applied Surface Science, 252 (19). pp. 6731-6733. ISSN 0169-4332

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Abstract

Aun+ and C60+ primary ion sources have been used to acquire spectra from phospholipids, symmetric liposomes and asymmetric liposomes. We demonstrate that when using different ion beams different chemical information can be obtained. Symmetric and asymmetric liposomes, with 95% asymmetry, were produced and analysed with Au+, Au3+ and C60+ primary ion beams. C60+ gave the greatest yield from the symmetric liposome but after correcting for the yield effects on the data obtained from the asymmetric liposome it has been shown that C60+ is the most surface sensitive, providing the least information from the inner leaflet of the liposome. Aun+ provides the greatest amount of information from the inner leaflet. The results present the possibility of designing ToF-SIMS experiments that selectively probe specific regions of a (bio)molecular surface.