Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

Baker, Matthew J. and Brown, Michael D. and Gazi, Ehsan and Clarke, Noel W. and Vickerman, John C. and Lockyer, Nicholas P. (2008) Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry. Analyst, 133 (2). pp. 175-179. ISSN 0003-2654

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Abstract

This communication utilises Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) combined with multivariate analysis to obtain spectra from the surfaces of three closely related cell lines allowing their discrimination based upon mass spectral ions.