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Open Access research which pushes advances in bionanotechnology

Strathprints makes available scholarly Open Access content by researchers in the Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS) , based within the Faculty of Science.

SIPBS is a major research centre in Scotland focusing on 'new medicines', 'better medicines' and 'better use of medicines'. This includes the exploration of nanoparticles and nanomedicines within the wider research agenda of bionanotechnology, in which the tools of nanotechnology are applied to solve biological problems. At SIPBS multidisciplinary approaches are also pursued to improve bioscience understanding of novel therapeutic targets with the aim of developing therapeutic interventions and the investigation, development and manufacture of drug substances and products.

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Rapid FTIR chemical imaging : highlighting FPA detectors

Dorling, Konrad M. and Baker, Matthew J. (2013) Rapid FTIR chemical imaging : highlighting FPA detectors. Trends in Biotechnology, 31 (8). pp. 437-438. ISSN 0167-7799

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Abstract

Fourier transform infrared (FTIR) spectroscopy is an established analytical technique that measures molecular bond vibrations via infrared absorption. The technique traditionally obtains single spectra from a sample, averaging the absorption information over a pre-determined aperture size. However, this averaging of information can be detrimental to pure biochemical analysis. The coupling of focal plane array (FPA) detectors to conventional FTIR systems and recent technical advances in FPA technology have allowed the concurrent rapid collection of thousands of infrared spectra over large areas of a sample, which has been particularly useful in tissue analysis. This novel technique presents a strong case for its use as a potential tool to aid in the clinic for disease diagnosis and assessment.