Picture of mobile phone running fintech app

Fintech: Open Access research exploring new frontiers in financial technology

Strathprints makes available Open Access scholarly outputs by the Department of Accounting & Finance at Strathclyde. Particular research specialisms include financial risk management and investment strategies.

The Department also hosts the Centre for Financial Regulation and Innovation (CeFRI), demonstrating research expertise in fintech and capital markets. It also aims to provide a strategic link between academia, policy-makers, regulators and other financial industry participants.

Explore all Strathclyde Open Access research...

Fabrication of 3D mili-scale channels of hemodynamic studies

Doutel, E. and Carneiro, J. and Oliveira, Monica and Campos, J.B.L.M. and Miranda, J.M. (2015) Fabrication of 3D mili-scale channels of hemodynamic studies. Journal of Mechanics in Medicine and Biology, 15 (1). ISSN 0219-5194

[img] PDF (Doutel E et al - Pure - Fabrication of 3D mili-scale channels for hemodynamic studies)
Doutel_E_et_al_Pure_Fabrication_of_3D_mili_scale_channels_for_hemodynamic_studies.pdf
Accepted Author Manuscript

Download (1MB)

Abstract

3D mili-scale channel representing simplified anatomical models of blood vessels were constructed in polidimethylsiloxane (PDMS). The objective was to obtain a sequential method to fabricate transparent PDMS models from a mold produced by rapid prototyping. For this purpose, two types of casting methods were compared, a known lost-wax casting method and a casting method using sucrose. The channels fabricated by both casting methods were analysed by Optical Microscopy, Scanning Electron Microscopy (SEM) and Energy Dispersive X-Ray Spectroscopy (EDS). The lost-wax method is not ideal since the channels become contaminated during the removal process. The models produced with the lost-sucrose casting method exhibit much better optical characteristics. These models are transparent with no visible contamination, since the removing process is done by dissolution at room temperature rather than melting. They allow for good optical access for flow visualization and measurement of the velocity field by micro-particle image velocimetry (μPIV). The channels fabricated by the lost-sucrose casting method were shown to be suitable for future hemodynamic studies using optical techniques.