Convergence of linkage, association and GWAS findings for a candidate region for bipolar disorder and schizophrenia on chromosome 4p
Christoforou, A and McGhee, K A and Morris, S W and Thomson, P A and McLean, A and Torrance, H S and Le Hellard, S and Pickard, B S and StClair, D and Muir, W J and Blackwood, D H and Porteous, D J and Evans, K L (2011) Convergence of linkage, association and GWAS findings for a candidate region for bipolar disorder and schizophrenia on chromosome 4p. Molecular Psychiatry, 16 (3). pp. 240-242. ISSN 1359-4184
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Several strong candidate genes and regions have been implicated in bipolar disorder (BP) and schizophrenia (SCZ) through linkage and association studies. These disorders have also recently been studied in genome-wide association studies (GWAS), identifying further putative candidate loci, albeit with lower levels of significance and reproducibility than in GWAS of other complex disorders.
Creators(s): |
Christoforou, A, McGhee, K A, Morris, S W, Thomson, P A, McLean, A, Torrance, H S, Le Hellard, S, Pickard, B S ![]() | Item type: | Article |
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ID code: | 49474 |
Keywords: | bipolar disorder, chromosome mapping, Pair 4, genetic linkage , genome-wide association study, humans, phenotype, polymorphism, single nucleotide, receptors, cell surface, schizophrenia, Neuroscience. Biological psychiatry. Neuropsychiatry, Cellular and Molecular Neuroscience, Molecular Biology, Psychiatry and Mental health |
Subjects: | Medicine > Internal medicine > Neuroscience. Biological psychiatry. Neuropsychiatry |
Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
Depositing user: | Pure Administrator |
Date deposited: | 01 Oct 2014 15:11 |
Last modified: | 01 Jan 2021 05:16 |
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URI: | https://strathprints.strath.ac.uk/id/eprint/49474 |
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