New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp

Pedpradab, Suwigarn and Edrada, RuAngelie and Ebel, Rainer and Wray, Victor and Proksch, Peter and Edrada-Ebel, Ruangelie (2004) New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp. Journal of Natural Products, 67 (12). pp. 2113-2116. ISSN 0163-3864 (https://doi.org/10.1021/np0401516)

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Abstract

Chemical investigation of the hithertho undescribed sponge Dragmacidon sp. from the Andaman Sea afforded two new beta-carboline alkaloids, which were named dragmacidonamines A (1) and B (2). The structures of the new compounds were unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H detected direct, and long-range 13C-1H correlations) and mass spectrometric (EI and ESIMS) data. The 3-carboxylic-beta-carboline moiety and the thiomethylated imidazolinium unit as found in dragmacidonamines are very rarely encountered in nature.

ORCID iDs

Pedpradab, Suwigarn, Edrada, RuAngelie, Ebel, Rainer, Wray, Victor, Proksch, Peter and Edrada-Ebel, Ruangelie ORCID logoORCID: https://orcid.org/0000-0003-2420-1117;