New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp
Pedpradab, Suwigarn and Edrada, RuAngelie and Ebel, Rainer and Wray, Victor and Proksch, Peter and Edrada-Ebel, Ruangelie (2004) New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp. Journal of Natural Products, 67 (12). pp. 2113-2116. ISSN 0163-3864 (https://doi.org/10.1021/np0401516)
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Chemical investigation of the hithertho undescribed sponge Dragmacidon sp. from the Andaman Sea afforded two new beta-carboline alkaloids, which were named dragmacidonamines A (1) and B (2). The structures of the new compounds were unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H detected direct, and long-range 13C-1H correlations) and mass spectrometric (EI and ESIMS) data. The 3-carboxylic-beta-carboline moiety and the thiomethylated imidazolinium unit as found in dragmacidonamines are very rarely encountered in nature.
ORCID iDs
Pedpradab, Suwigarn, Edrada, RuAngelie, Ebel, Rainer, Wray, Victor, Proksch, Peter and Edrada-Ebel, Ruangelie
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Item type: Article ID code: 48436 Dates: DateEventDecember 2004PublishedSubjects: Medicine > Therapeutics. Pharmacology Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Depositing user: Pure Administrator Date deposited: 05 Jun 2014 12:02 Last modified: 31 Jan 2025 23:40 URI: https://strathprints.strath.ac.uk/id/eprint/48436