Integrated microfluidic spectroscopic sensor using arrayed waveguide grating

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Hu, Zhixiong and Glidle, Andrew and Ironside, Charles N. and Sorel, Marc M. and Strain, Michael John and Cooper, Jonathan M. and Yin, Huabing H. (2013) Integrated microfluidic spectroscopic sensor using arrayed waveguide grating. Proceedings of SPIE - The International Society for Optical Engineering, 8911. 89110A. ISSN 1996-756X (https://doi.org/10.1117/12.2033213)

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Abstract

With non-invasive properties and high sensitivities, portable optical biosensors are extremely desirable for point-of-care (POC) applications. Lab-on-a-chip technology such as microfluidics has been treated as an ideal approach to integrate complex sample processing and analysis units with optical detection elements. The work in this paper has developed an integrated dispersive component in combination with a microfluidic chip, providing a portable and inexpensive platform for on-chip spectroscopic sensing. We demonstrate an integrated microfluidic spectroscopic sensor by using an arrayed waveguide grating (AWG) device. In particular, a visible AWG device (λc=680nm) with chip size of 12.1mm by 1.5mm was designed and fabricated by employing flamed hydrolysis deposited (FHD) silica as the waveguide material. A straight input waveguide is used to perform device characterization while a perpendicular curved waveguide is employed to introduce laser excitation light. A polymer microfluidic chip is integrated with the AWG device by oxygen plasma bonding. To prove effectiveness of the integrated spectroscopic sensor, fluorescence spectrum of an organic fluorophore (Cy5) was tested. Reconstructed spectrum by using the AWG device is compared with the outcome from a conventional spectrometer and a good consistency is presented.

ORCID iDs

Hu, Zhixiong, Glidle, Andrew, Ironside, Charles N., Sorel, Marc M., Strain, Michael John ORCID logoORCID: https://orcid.org/0000-0002-9752-3144, Cooper, Jonathan M. and Yin, Huabing H.;
  • Item type:Article
    ID code:47885
    Dates:
    Date
    Event
    1 January 2013
    Published
    Notes:From Conference Volume 8911, International Symposium on Photoelectronic Detection and Imaging 2013: Micro/Nano Optical Imaging Technologies and Applications. Min Gu; Xiaocong Yuan; Min Qiu. Beijing, China | June 25, 2013
    Subjects:Science > Physics > Optics. Light
    Department:Faculty of Science > Physics > Institute of Photonics
    Depositing user: Pure Administrator
    Date deposited:07 May 2014 13:09
    Last modified:11 Nov 2024 10:41
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/47885
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