Prognostic significance of being overweight and obese at diagnosis in children with acute lymphoblastic leukemia

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Aldhafiri, F.K. and McColl, J.H. and Reilly, J.J. (2014) Prognostic significance of being overweight and obese at diagnosis in children with acute lymphoblastic leukemia. Journal of Pediatric Hematology/Oncology, 36 (3). pp. 234-236. ISSN 1077-4114 (https://doi.org/10.1097/MPH.0000000000000056)

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Abstract

This study tested the hypothesis that being overweight/obese at diagnosis of childhood ALL was related to risk of relapse. In a national cohort of 1033 patients from the UK, there was no evidence that weight status at diagnosis was related significantly to risk of relapse: log-rank test (P=0.90) with overweight and obesity as the exposure (n=917); individual (P=0.42) and stepwise (P=0.96) proportional hazards models, with BMI Z score as the exposure. The study does not support the hypothesis that being overweight/obese at diagnosis impairs prognosis in childhood ALL in the UK.

ORCID iDs

Aldhafiri, F.K., McColl, J.H. and Reilly, J.J. ORCID logoORCID: https://orcid.org/0000-0001-6165-5471;
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