Modifying alkylzinc reactivity with 2,2 '-dipyridylamide : activation of tBu-Zn bonds for para-alkylation of benzophenone

Armstrong, David R. and Garden, Jennifer A. and Kennedy, Alan R. and Mulvey, Robert and Robertson, Stuart D. (2013) Modifying alkylzinc reactivity with 2,2 '-dipyridylamide : activation of tBu-Zn bonds for para-alkylation of benzophenone. Angewandte Chemie International Edition, 52 (28). pp. 7190-7193. ISSN 1433-7851

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    Abstract

    Undercover agent: Masquerading as a simple donor-acceptor complex (1), sodium amide substoichiometrically activates tBuZn for the challenging 1,6-addition of a tert-butyl group to benzophenone. In contrast, the nonactivated tBuZn is ineffectual.

    ORCID iDs

    Armstrong, David R., Garden, Jennifer A., Kennedy, Alan R., Mulvey, Robert ORCID logoORCID: https://orcid.org/0000-0002-1015-2564 and Robertson, Stuart D. ORCID logoORCID: https://orcid.org/0000-0002-9330-8770;
    • Item type:Article
      ID code:44630
      Dates:
      Date
      Event
      8 July 2013
      Published
      5 June 2013
      Published Online
      Keywords:zinc, reagents, ligands, alkylation, metalation, alkali metal, crystal-structure, dipyridylamine, chloride, 2,2-dipyridylamine, sodium TMP-zincate, chemistry, homogeneous catalysis, amides, complexes, Chemistry, Chemistry(all), Biochemistry
      Subjects:Science > Chemistry
      Department:Faculty of Science > Pure and Applied Chemistry
      Depositing user: Pure Administrator
      Date deposited:28 Aug 2013 13:39
      Last modified:08 Jun 2021 00:23
      Related URLs:
      URI:https://strathprints.strath.ac.uk/id/eprint/44630
    CORE (COnnecting REpositories)