Modifying alkylzinc reactivity with 2,2 '-dipyridylamide : activation of tBu-Zn bonds for para-alkylation of benzophenone
Armstrong, David R. and Garden, Jennifer A. and Kennedy, Alan R. and Mulvey, Robert and Robertson, Stuart D. (2013) Modifying alkylzinc reactivity with 2,2 '-dipyridylamide : activation of tBu-Zn bonds for para-alkylation of benzophenone. Angewandte Chemie International Edition, 52 (28). pp. 7190-7193. ISSN 1433-7851 (https://doi.org/10.1002/anie.201302426)
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Abstract
Undercover agent: Masquerading as a simple donor-acceptor complex (1), sodium amide substoichiometrically activates tBuZn for the challenging 1,6-addition of a tert-butyl group to benzophenone. In contrast, the nonactivated tBuZn is ineffectual.
ORCID iDs
Armstrong, David R., Garden, Jennifer A., Kennedy, Alan R., Mulvey, Robert

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Item type: Article ID code: 44630 Dates: DateEvent8 July 2013Published5 June 2013Published OnlineKeywords: zinc, reagents, ligands, alkylation, metalation, alkali metal, crystal-structure, dipyridylamine, chloride, 2,2-dipyridylamine, sodium TMP-zincate, chemistry, homogeneous catalysis, amides, complexes, Chemistry, Chemistry(all), Biochemistry Subjects: Science > Chemistry Department: Faculty of Science > Pure and Applied Chemistry Depositing user: Pure Administrator Date deposited: 28 Aug 2013 13:39 Last modified: 07 May 2022 00:12 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/44630
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