Bioresponsive hydrogels
Ulijn, Rein V. and Bibi, Nurguse and Jayawarna, Vineetha and Thornton, Paul D. and Todd, Simon J. and Mart, Robert J. and Smith, Andrew M. and Gough, Julie E. (2007) Bioresponsive hydrogels. Materials Today, 10 (4). pp. 40-48. ISSN 1369-7021
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We highlight recent developments in hydrogel materials with biological responsiveness built in. These 'smart' biomaterials change properties in response to selective biological recognition events. When exposed to a biological target (nutrient, growth factor, receptor, antibody, enzyme, or whole cell), molecular recognition events trigger changes in molecular interactions that translate into macroscopic responses, such as swelling/collapse or solution-to-gel transitions. The hydrogel transitions may be used directly as optical readouts for biosensing, linked to the release of actives for drug delivery, or instigate biochemical signaling events that control or direct cellular behavior. Accordingly, bioresponsive hydrogels have gained significant interest for application in diagnostics, drug delivery, and tissue regeneration/wound healing.
| Creators(s): |
Ulijn, Rein V.  ORCID: https://orcid.org/0000-0001-7974-3779, Bibi, Nurguse, Jayawarna, Vineetha ORCID: https://orcid.org/0000-0002-2936-6634, Thornton, Paul D., Todd, Simon J., Mart, Robert J., Smith, Andrew M. and Gough, Julie E.;
| Item type: | Article |
|---|---|
| ID code: | 43949 |
| Keywords: | bioresponsive hydrogels, photonic crystal, supramolecular hydrogel, responsive polymers, sensitive hydrogels, cell migration, drug delivery, in vivo, biomaterials, glucose, medicine, Chemistry, Electrical engineering. Electronics Nuclear engineering, Mechanics of Materials, Materials Science(all), Mechanical Engineering, Condensed Matter Physics |
| Subjects: | Science > Chemistry Technology > Electrical engineering. Electronics Nuclear engineering |
| Department: | Faculty of Science > Pure and Applied Chemistry Faculty of Engineering > Electronic and Electrical Engineering |
| Depositing user: | Pure Administrator |
| Date deposited: | 30 May 2013 11:53 |
| Last modified: | 18 Sep 2020 04:04 |
| URI: | https://strathprints.strath.ac.uk/id/eprint/43949 |
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