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Bioresponsive hydrogels

Ulijn, Rein V. and Bibi, Nurguse and Jayawarna, Vineetha and Thornton, Paul D. and Todd, Simon J. and Mart, Robert J. and Smith, Andrew M. and Gough, Julie E. (2007) Bioresponsive hydrogels. Materials Today, 10 (4). pp. 40-48. ISSN 1369-7021

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Abstract

We highlight recent developments in hydrogel materials with biological responsiveness built in. These 'smart' biomaterials change properties in response to selective biological recognition events. When exposed to a biological target (nutrient, growth factor, receptor, antibody, enzyme, or whole cell), molecular recognition events trigger changes in molecular interactions that translate into macroscopic responses, such as swelling/collapse or solution-to-gel transitions. The hydrogel transitions may be used directly as optical readouts for biosensing, linked to the release of actives for drug delivery, or instigate biochemical signaling events that control or direct cellular behavior. Accordingly, bioresponsive hydrogels have gained significant interest for application in diagnostics, drug delivery, and tissue regeneration/wound healing.

Item type: Article
ID code: 43949
Keywords: bioresponsive hydrogels, photonic crystal, supramolecular hydrogel, responsive polymers, sensitive hydrogels, cell migration, drug delivery, in vivo, biomaterials, glucose, medicine, Chemistry, Electrical engineering. Electronics Nuclear engineering, Mechanics of Materials, Materials Science(all), Mechanical Engineering, Condensed Matter Physics
Subjects: Science > Chemistry
Technology > Electrical engineering. Electronics Nuclear engineering
Department: Faculty of Science > Pure and Applied Chemistry
Faculty of Engineering > Electronic and Electrical Engineering
Depositing user: Pure Administrator
Date deposited: 30 May 2013 11:53
Last modified: 19 Apr 2019 02:23
URI: https://strathprints.strath.ac.uk/id/eprint/43949
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