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Driving innovations in manufacturing: Open Access research from DMEM

Strathprints makes available Open Access scholarly outputs by Strathclyde's Department of Design, Manufacture & Engineering Management (DMEM).

Centred on the vision of 'Delivering Total Engineering', DMEM is a centre for excellence in the processes, systems and technologies needed to support and enable engineering from concept to remanufacture. From user-centred design to sustainable design, from manufacturing operations to remanufacturing, from advanced materials research to systems engineering.

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Minimally-invasive optoelectronic sensing technique for chemical analysis of aqueous humour

Blue, Robert and Uttamchandani, Deepak and Wilson, C. G. (1999) Minimally-invasive optoelectronic sensing technique for chemical analysis of aqueous humour. IEE Proceedings Science Measurement and Technology, 146 (1). 41 - 46. ISSN 1350-2344

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Abstract

The determination of the concentration of drugs and other compounds within the anterior chamber of the eye is a measurement of great interest in ophthalmic science. A minimally invasive optoelectronic technique to identify and measure various compounds using absorption and fluorescence spectroscopy, and involving fibre optics, is described. These experiments demonstrate the technical feasibility of an optoelectronic instrument for drug concentration estimation in the anterior chamber by employing absorption measurements. Both model and real animal eyes were used in the experiments. Compounds such as fluorescein and tetracycline, the latter a commonly used antibiotic for ophthalmic applications, have been detected in the anterior chamber of perfused animal eyes using this technique