Effectiveness of seasonal 2012/13 vaccine in preventing laboratory-confirmed influenza infection in primary care in the United Kingdom: : mid-season analysis 2012/13

McMenamin, J. and Andrews, N. and Robertson, Charles and Fleming, D.M. and Durnall, H. and von Wissmann, B. and Ellis, J and Lackenby, A. and Cottrell, S. and Smyth, B. and Zambon, Maria and Moore, C. and Watson, J. M. and Pebody, R.G. (2013) Effectiveness of seasonal 2012/13 vaccine in preventing laboratory-confirmed influenza infection in primary care in the United Kingdom: : mid-season analysis 2012/13. Eurosurveillance, 18 (5). 1. ISSN 1560-7917

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Abstract

The early experience of the United Kingdom (UK) is that influenza B has dominated the influenza 2012/13 season. Overall trivalent influenza vaccine (TIV) adjusted vaccine effectiveness (VE) against all laboratory-confirmed influenza in primary care was 51% (95% confidence interval (CI): 27% to 68%); TIV adjusted VE against influenza A alone or influenza B alone was 49% (95% CI: -2% to 75%) and 52% (95% CI: 23% to 70%) respectively. Vaccination remains the best protection against influenza.