Glucose uptake stimulatory effect of akuammicine from picralima nitida (Apocynaceae)

Shittu, H and Gray, Alexander and Furman, Brian and Young, Louise (2010) Glucose uptake stimulatory effect of akuammicine from picralima nitida (Apocynaceae). Phytochemistry Letters, 3 (1). pp. 53-55. (https://doi.org/10.1016/j.phytol.2009.11.003)

Abstract

A bioactivity-guided fractionation of the chloroform extract of the seeds of Picralima nitida using glucose uptake in fully differentiated 3T3-L1 adipocytes afforded six indole alkaloids (akuammicine, 10-deoxyakuammine, akuammine, akuammidine, burnamine and picraline) and a mixture of four 5-hydroxy tryptamine amides. Akuammicine accounted for the increase in glucose uptake observed in the chloroform extract. (C) 2009 Phytochemical Society of Europe.

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• Item metadata

  Item type:	Article
  ID code:	41172
  Dates:	Date Event 12 March 2010 Published
  Subjects:	Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	18 Sep 2012 13:47
  Last modified:	31 Jan 2025 08:00
  URI:	https://strathprints.strath.ac.uk/id/eprint/41172