Glucose uptake stimulatory effect of akuammicine from picralima nitida (Apocynaceae)

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Shittu, H and Gray, Alexander and Furman, Brian and Young, Louise (2010) Glucose uptake stimulatory effect of akuammicine from picralima nitida (Apocynaceae). Phytochemistry Letters, 3 (1). pp. 53-55. (https://doi.org/10.1016/j.phytol.2009.11.003)

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Abstract

A bioactivity-guided fractionation of the chloroform extract of the seeds of Picralima nitida using glucose uptake in fully differentiated 3T3-L1 adipocytes afforded six indole alkaloids (akuammicine, 10-deoxyakuammine, akuammine, akuammidine, burnamine and picraline) and a mixture of four 5-hydroxy tryptamine amides. Akuammicine accounted for the increase in glucose uptake observed in the chloroform extract. (C) 2009 Phytochemical Society of Europe.

ORCID iDs

Shittu, H, Gray, Alexander, Furman, Brian and Young, Louise ORCID logoORCID: https://orcid.org/0000-0003-1757-6404;
CORE (COnnecting REpositories)