A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle
DeCoursey, T.E. and Dempster, John and Hutter, O.F. (1982) A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle. Journal of Physiology, 329 (Suppl.). P7-P8. ISSN 0022-3751
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The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.
| Author(s): | DeCoursey, T.E., Dempster, John  ORCID: https://orcid.org/0000-0003-2199-2945 and Hutter, O.F. | Item type: | Article |
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| ID code: | 40254 |
| Keywords: | voltage, frog skeletal muscle, voltage-clamp experiments, Pharmacy and materia medica, Physiology |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Depositing user: | Pure Administrator |
| Date deposited: | 29 Jun 2012 10:11 |
| Last modified: | 02 Dec 2019 10:07 |
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| URI: | https://strathprints.strath.ac.uk/id/eprint/40254 |
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