A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle

DeCoursey, T.E. and Dempster, John and Hutter, O.F. (1982) A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle. Journal of Physiology, 329 (Suppl.). P7-P8. ISSN 0022-3751

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Abstract

The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.

Creators(s): DeCoursey, T.E., Dempster, John ORCID logoORCID: https://orcid.org/0000-0003-2199-2945 and Hutter, O.F.;
Item type:Article
ID code:40254
Keywords:voltage, frog skeletal muscle, voltage-clamp experiments, Pharmacy and materia medica, Physiology
Subjects:Medicine > Pharmacy and materia medica
Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Depositing user: Pure Administrator
Date deposited:29 Jun 2012 10:11
Last modified:02 Dec 2020 02:07
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URI:https://strathprints.strath.ac.uk/id/eprint/40254
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