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Open Access research with a European policy impact...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the European Policies Research Centre (EPRC).

EPRC is a leading institute in Europe for comparative research on public policy, with a particular focus on regional development policies. Spanning 30 European countries, EPRC research programmes have a strong emphasis on applied research and knowledge exchange, including the provision of policy advice to EU institutions and national and sub-national government authorities throughout Europe.

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A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle

DeCoursey, T.E. and Dempster, John and Hutter, O.F. (1982) A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle. Journal of Physiology, 329 (Suppl.). P7-P8. ISSN 0022-3751

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Abstract

The inwardly rectifying potassium conductance in frog skeletal muscle resides largely in the transverse tubular system (TTS). In voltage-clamp experiments, the membrane potential of the TTS will in general not be the same as the surface potential, owing to voltage drop across the tubular luminal resistance; hence the measured total conductance-voltage relation is liable to differ from the intrinsic rectifying function.