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Pioneering chemical biology & medicinal chemistry through Open Access research...

Strathprints makes available scholarly Open Access content by researchers in the Department of Pure & Applied Chemistry, based within the Faculty of Science.

Research here spans a wide range of topics from analytical chemistry to materials science, and from biological chemistry to theoretical chemistry. The specific work in chemical biology and medicinal chemistry, as an example, encompasses pioneering techniques in synthesis, bioinformatics, nucleic acid chemistry, amino acid chemistry, heterocyclic chemistry, biophysical chemistry and NMR spectroscopy.

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The use of targeted radionuclide therapy for the treatment of malignant melanoma in vivo

Joyce, C. and Boyd, M. and Sorensen, A. and Tesson, M. and Babich, J. W. and Mairs, R. J. (2012) The use of targeted radionuclide therapy for the treatment of malignant melanoma in vivo. Mutagenesis, 27 (1). p. 110. ISSN 0267-8357

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Abstract

This study investigates the potential of the noradrenaline analogue [131I]MIBG (metaiodobenzylguanidine) and the novel melanin binding benzamide [131I] Solazed for melanoma therapy in vivo and in vitro.