Targeted dendrimers

Dufès, Christine (2011) Targeted dendrimers. A61K 47/48.

Abstract

The present invention relates to a composition for targeted delivery of a bioactive molecule to cells in a body of a recipient, said composition comprising a polypropylenimine dendrimer and/or derivatives thereof to which one or more cell targeting molecule (s) have been conjugated thereto; and a bioactive molecule associated with said polypropylenimine dendrimer and/or derivative thereof. In one embodiment the cells to be targeted are cancer cells. The targeting molecule may be transferrin, lactoferrin, lactoferricin or gambogic acid. There is also provided uses of such compositions, as well as methods of treating diseases, such as cancer.

ORCID iDs

Dufès, Christine ORCID: https://orcid.org/0000-0002-7963-6364

• Share and Export
  

  RDF+XMLBibTeXRIOXX2 XMLRDF+N-TriplesJSONDublin CoreAtomSimple MetadataReferMETSHTML CitationASCII CitationOpenURL ContextObjectEndNoteOpenURL ContextObject in SpanMODSMPEG-21 DIDLEP3 XMLData Cite XMLRIS (EndNote Online, Zotero, Ref manager, etc)RDF+N3Multiline CSV
• Citations and altmetrics
• Item metadata

  Item type:	Patent
  ID code:	39723
  Dates:	Date Event 5 May 2011 Published
  Notes:	Patent Application
  Keywords:	bioactive molecule, polypropylenimine dendrimer, cell targeting, cancer cells, Therapeutics. Pharmacology, SDG 3 - Good Health and Well-being
  Subjects:	Medicine > Therapeutics. Pharmacology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Technology and Innovation Centre > Bionanotechnology
  Depositing user:	Pure Administrator
  Date deposited:	16 May 2012 10:50
  Last modified:	18 Jan 2023 12:05
  Related URLs:	Journal or Publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/39723