Picture of blood cells

Open Access research which pushes advances in bionanotechnology

Strathprints makes available scholarly Open Access content by researchers in the Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS) , based within the Faculty of Science.

SIPBS is a major research centre in Scotland focusing on 'new medicines', 'better medicines' and 'better use of medicines'. This includes the exploration of nanoparticles and nanomedicines within the wider research agenda of bionanotechnology, in which the tools of nanotechnology are applied to solve biological problems. At SIPBS multidisciplinary approaches are also pursued to improve bioscience understanding of novel therapeutic targets with the aim of developing therapeutic interventions and the investigation, development and manufacture of drug substances and products.

Explore the Open Access research of SIPBS. Or explore all of Strathclyde's Open Access research...

Bactericidal effect of corona discharges in atmospheric air

Timoshkin, Igor and Maclean, Michelle and Wilson, Mark and Given, M and MacGregor, Scott and Wang, Tao and Anderson, John (2012) Bactericidal effect of corona discharges in atmospheric air. IEEE Transactions on Plasma Science, 40 (10). 2322 - 2333. ISSN 0093-3813

Accepted Author Manuscript

Download (370kB)| Preview


    The present paper explores the possibilities of using impulsive and steady-state corona discharges for bio-decontamination operations. A high tension tubular corona electrode was stressed with positive or negative dc voltage with magnitude up to 26 kV, and a grounded mesh was used as an opposite electrode. Different operational regimes of this corona generator were investigated for the production of ozone in air flow and the inactivation of microorganisms. The test microorganisms used in this work were Escherichia coli and Staphylococcus aureus, populations of which were seeded onto agar plates. These bacterial plates were located behind the grounded mesh electrode to assess bactericidal efficacy. The results show that corona discharges have a strong bactericidal effect, for example positive flashing corona discharges were able to reduce populations of the test microorganism by 94% within a 30-60 sec time interval. Negative steady-state corona discharges also produce noticeable bactericidal effect, reducing population of E. coli and S. aureus by more than 97% within 120 sec energisation interval. The bactericidal efficiency of different corona discharge modes and its correlation with ozone levels produced by these discharges is discussed. The results obtained in this work will help in the design and development of compact plasma systems for environmental applications