System analysis of a programmed cell death model
Bullinger, Eric (2006) System analysis of a programmed cell death model. In: 44th IEEE Conference on Decision and Control and European Control Conference, 2005-12-12 - 2005-12-15. (https://doi.org/10.1109/CDC.2005.1583455)
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Apoptosis is a programmed cell death by which the organism removes unwanted cells. Its core reactions can be described by a system of differential equations exhibiting multiple steady-states. In this paper we analyse how this model can include both very slow dynamics for the lag phase before apoptosis (in theory up to several days) while the apoptosis itself is more switch-like with changes occurring within minutes. We both describe how the trajectories evolve during the lag phase and show which of the states have the most impact on the slow dynamics.
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Item type: Conference or Workshop Item(Paper) ID code: 37584 Dates: DateEvent2006PublishedSubjects: Technology > Electrical engineering. Electronics Nuclear engineering Department: Faculty of Engineering > Electronic and Electrical Engineering Depositing user: Pure Administrator Date deposited: 10 Feb 2012 16:21 Last modified: 11 Nov 2024 16:21 URI: https://strathprints.strath.ac.uk/id/eprint/37584