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Pixel detectors for use in retina neurophysiology studies

Cunningham, W and Mathieson, K and Horn, M and Melone, J and McEwan, FA and Blue, A and O'Shea, V and Smith, KM and Litke, A and Chichilnisky, EJ and Rahman, M (2003) Pixel detectors for use in retina neurophysiology studies. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 509 (1-3). pp. 235-239. ISSN 0168-9002

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Abstract

One area of major inter-disciplinary co-operation is between the particle physics and bio-medical communities. The type of large detector arrays and fast electronics developed in laboratories like CERN are becoming used for a wide range of medical and biological experiments. In the present work fabrication technology developed for producing semiconductor radiation detectors has been applied to produce arrays which have been used in neuro-physiological experiments on retinal tissue. We have exploited UVIII, a low molecular weight resist, that has permitted large area electron beam lithography. This allows the resolution to go below that of conventional photolithography and hence the production of densely packed ∼500 electrode arrays with feature sizes down to below . The neural signals from significant areas of the retina may thus be captured.