System and control theory furthers the understanding of biological signal transduction

Bullinger, Eric and Findeisen, R. and Kalamatianos, D. and Wellstead, P.; (2007) System and control theory furthers the understanding of biological signal transduction. In: Biology and Control Theory: Current Challenges. Lecture Notes in Control and Information Sciences . UNSPECIFIED, pp. 123-135. ISBN 978-3-540-71987-8

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Abstract

This article discusses why novel modelling and analysis methods are required for biological systems, presents recent advances and outlines some future challenges. In this respect, the main focus is placed upon methods for parameter estimation and sensitivity analysis as they are encountered in systems biology.