Towards the total synthesis of Agariblazeispirol C.

Paterson, Laura C. and Kerr, William J. and Sutherland, Andrew. (2009) Towards the total synthesis of Agariblazeispirol C. In: WestCHEM Postgraduate Symposium in Organic Chemistry, 2009-06-19.

Abstract

Efforts within our lab. have focused towards the synthesis of Agariblazeispirol C, 1, which was recently isolated from the cultured mycelia of Agaricus blazei. Our proposed pathway for gaining access to Agariblazeispirol C centers on the strategic employment of metal-mediated cyclisation chem. Specifically, an . Pauson-Khand reaction (PKR) will be used to construct the C/D ring section of the natural target, and a novel intramol. Heck reaction will establish the key all carbon quaternary center between rings B and C.

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• Item metadata

  Item type:	Conference or Workshop Item(Other)
  ID code:	35030
  Dates:	Date Event 19 June 2009 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Pure Administrator
  Date deposited:	24 Oct 2011 09:59
  Last modified:	09 Apr 2024 05:37
  Related URLs:	Department
  URI:	https://strathprints.strath.ac.uk/id/eprint/35030