Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4′-methylmethcathinone (mephedrone) : a new "legal high"
Santali, Eman Y. and Cadogan, Anna-Karina and Daeid, Niamh Nic and Savage, Kathleen A. and Sutcliffe, Oliver B. (2011) Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4′-methylmethcathinone (mephedrone) : a new "legal high". Journal of Pharmaceutical and Biomedical Analysis, 56 (2). pp. 246-255. ISSN 1873-264X (https://doi.org/10.1016/j.jpba.2011.05.022)
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The recent global increase in the abuse of 4'-methylmethcathinone and related compounds has developed a requirement for full chemical characterisation of these products. In this work we present full synthetic and chemical characterisation data and supplemental information for mephedrone synthesised as both the hydrobromide and hydrochloride salt. Additionally we report the first fully validated chromatographic methods for the detection and quantitative analysis of the substance both in its pure form and in the presence of a number of common adulterants used in illicit drug manufacture.
ORCID iDs
Santali, Eman Y. ORCID: https://orcid.org/0000-0003-0923-2310, Cadogan, Anna-Karina, Daeid, Niamh Nic, Savage, Kathleen A. ORCID: https://orcid.org/0000-0003-3969-9982 and Sutcliffe, Oliver B.;-
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Item type: Article ID code: 33453 Dates: DateEvent10 September 2011PublishedNotes: Copyright © 2011 Elsevier B.V. All rights reserved. Subjects: Science > Chemistry Department: Faculty of Science > Pure and Applied Chemistry
Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical SciencesDepositing user: Pure Administrator Date deposited: 19 Sep 2011 09:13 Last modified: 11 Nov 2024 09:50 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/33453