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Open Access research which pushes advances in bionanotechnology

Strathprints makes available scholarly Open Access content by researchers in the Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS) , based within the Faculty of Science.

SIPBS is a major research centre in Scotland focusing on 'new medicines', 'better medicines' and 'better use of medicines'. This includes the exploration of nanoparticles and nanomedicines within the wider research agenda of bionanotechnology, in which the tools of nanotechnology are applied to solve biological problems. At SIPBS multidisciplinary approaches are also pursued to improve bioscience understanding of novel therapeutic targets with the aim of developing therapeutic interventions and the investigation, development and manufacture of drug substances and products.

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Automatic motion feature extraction with application to quantitative assessment of facial paralysis

He, Shu and Soraghan, John and O'Reilly, Brian F (2007) Automatic motion feature extraction with application to quantitative assessment of facial paralysis. In: 2007 IEEE International conference on acoustics, speech and signal processing, Volume I, Parts 1-3, Proceedings. International Conference on Acoustics Speech and Signal Processing (ICASSP) . IEEE, New York, pp. 441-444. ISBN 9781424407286

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This paper presents a robust, objective, automated and quantitative assessment system for Facial Paralysis using artificial intelligence analysis of biomedial video data. Facial feature localization and prescribed facial movements detection are discussed. Optical flow is used to obtain the motion features in the relevant facial regions. Radial Basis Function (RBF) Neural Network is applied to provide quantitative evaluation of Facial Paralysis based on the House-Brackmann Scale. The results from 197 videos of 87 subjects are encouraging with a Mean Squared Error (MSE) of 0.013 (training) and 0.0169 (testing).