Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis

Milner, J. M. and Patel, A. and Davidson, R. K. and Swingler, T. E. and Desilets, A. and Young, D. A. and Kelso, E. B. and Donell, S. T. and Cawston, T. E. and Clark, I. M. and Ferrell, W. R. and Plevin, R. and Lockhart, J. C. and Leduc, R. and Rowan, A. D. (2010) Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. [Review]

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Abstract

Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).

Creators(s): Milner, J. M., Patel, A., Davidson, R. K., Swingler, T. E., Desilets, A., Young, D. A. ORCID logoORCID: https://orcid.org/0000-0002-3494-1242, Kelso, E. B., Donell, S. T., Cawston, T. E., Clark, I. M. ORCID logoORCID: https://orcid.org/0000-0002-2805-9544, Ferrell, W. R., Plevin, R. ORCID logoORCID: https://orcid.org/0000-0002-7849-1220, Lockhart, J. C., Leduc, R. and Rowan, A. D.;
Item type:Review
ID code:31768
Keywords:osteoarthritis, cartilage destruction , matriptase, Pharmacy and materia medica, Cell Biology, Molecular Biology, Pathology and Forensic Medicine
Subjects:Medicine > Pharmacy and materia medica
Department:Faculty of Science > Physics
Faculty of Humanities and Social Sciences (HaSS) > School of Humanities > English
Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Depositing user: Pure Administrator
Date deposited:22 Jun 2011 14:30
Last modified:15 Jul 2020 01:10
URI:https://strathprints.strath.ac.uk/id/eprint/31768
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