Omega-conotoxin does not block the verapamil-sensitive calcium channels at mouse motor nerve terminals
Anderson, A J and Harvey, A L (1987) Omega-conotoxin does not block the verapamil-sensitive calcium channels at mouse motor nerve terminals. Neuroscience Letters, 82 (2). pp. 177-180. ISSN 0304-3940
Full text not available in this repository.Request a copy from the Strathclyde authorAbstract
Release of acetylcholine at the neuromuscular junctions of skeletal muscle is not sensitive to organic Ca2+ channel blockers. However, in mouse motor nerve endings, extracellular recording reveals that a verapamil-sensitive Ca2+ current can be induced after block of K+ channels. Recordings of extracellular action potentials from inside the perineural sheaths of nerves innervating mouse triangularis sterni muscles reveal that this verapamil-sensitive current is not blocked by omega-conotoxin, and hence, it does not involve channels similar to the L-channels of neuronal cell bodies.
Creators(s): | Anderson, A J and Harvey, A L; | Item type: | Article |
---|---|
ID code: | 31690 |
Keywords: | animals, anura, calcium, ion channels, male, mice, inbred BALB C mice, mollusk venoms, nerve block, neuromuscular junction, verapamil, omega-conotoxins, Pharmacy and materia medica, Neuroscience(all) |
Subjects: | Medicine > Pharmacy and materia medica |
Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
Depositing user: | Pure Administrator |
Date deposited: | 13 Jul 2011 08:57 |
Last modified: | 20 Jan 2021 19:25 |
URI: | https://strathprints.strath.ac.uk/id/eprint/31690 |
Export data: |