Tryptase as a PAR-2 activator in joint inflammation

Kelso, E.B. and Dunning, L. and Lockhart, J.C. and Ferrell, W.R. and Plevin, R. and Sommerhoff, C.P. (2005) Tryptase as a PAR-2 activator in joint inflammation. In: 25th European Workshop for Rheumatology Research, 2005-02-24 - 2005-02-27. (http://dx.doi.org/10.1186/ar1620)

Abstract

Protease-activated receptor-2 (PAR-2) is one of a family of G-protein coupled transmembrane receptors activated by proteolytic release of a 'tethered' ligand. We previously reported this receptor has a pivotal role in chronic joint inflammation using a PAR-2 'knockout' mouse [1], but the serine protease responsible for its activation remains uncertain.

ORCID iDs

Plevin, R. ORCID: https://orcid.org/0000-0002-7849-1220

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• Item metadata

  Item type:	Conference or Workshop Item(Poster)
  ID code:	3131
  Dates:	Date Event 17 February 2005 Published
  Subjects:	Science > Physiology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Strathprints Administrator
  Date deposited:	17 Apr 2007
  Last modified:	11 Nov 2024 16:12
  URI:	https://strathprints.strath.ac.uk/id/eprint/3131