Metabolic sensing using fluorescence

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Birch, David J.S. and Ganesan, Ashok and Karolin, Jan (2005) Metabolic sensing using fluorescence. Synthetic Metals, 155 (2). pp. 410-413. ISSN 0379-6779 (https://doi.org/10.1016/j.synthmet.2005.09.025)

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Abstract

With a view to assessing the current boundaries of non-invasive sensing of metabolites we compare the photophysical properties of melanin nanoparticles in vivo, size selected in natural form from Sepia officinalis extracted from cuttlefish, and synthesised from L-dihydoxyphenylalanine (DOPA) in water pools of reverse micelles. The fluorescence emission spectra and excited state decay components correlate well with the particle size. Recent developments in optical technology are discussed in the context of the formidable challenges and opportunities for metabolic sensing presented by endogenous fluorophores.

ORCID iDs

Birch, David J.S. ORCID logoORCID: https://orcid.org/0000-0001-6400-1270, Ganesan, Ashok and Karolin, Jan;
  • Item type:Article
    ID code:31133
    Dates:
    Date
    Event
    15 November 2005
    Published
    Notes:6th International Topical Conference on Optical Probes of Conjugated Polymers and Biosystems, Bangalore, INDIA, JAN 04-08, 2005
    Subjects:Science > Physics
    Department:Faculty of Science > Physics
    Depositing user: Pure Administrator
    Date deposited:01 Jul 2011 09:22
    Last modified:11 Nov 2024 09:44
    URI:https://strathprints.strath.ac.uk/id/eprint/31133
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