Multipoint viscosity measurements in microfluidic channels using optical tweezers

Keen, Stephen and Yao, Alison and Leach, Jonathan and Di Leonardo, Roberto and Saunter, Chris and Love, Gordon and Cooper, Jonathan and Padgett, Miles (2009) Multipoint viscosity measurements in microfluidic channels using optical tweezers. Lab on a Chip, 9 (14). pp. 2059-2062. ISSN 1473-0197

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Abstract

We demonstrate the technique of multipoint viscosity measurements incorporating the accurate calibration of micron sized particles. We describe the use of a high-speed camera to measure the residual motion of particles trapped in holographic optical tweezers, enabling us to calculate the fluid viscosity at multiple points across the field-of-view of the microscope within a microfluidic system.