Diisopropylamide and TMP turbo-grignard reagents : a structural rationale for their contrasting reactivities

Armstrong, David R. and Garcia-Álvarez, Pablo and Kennedy, Alan R. and Mulvey, Robert E. and Parkinson, John A. (2010) Diisopropylamide and TMP turbo-grignard reagents : a structural rationale for their contrasting reactivities. Angewandte Chemie International Edition, 49 (18). 3185–3188. ISSN 1433-7851

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      Abstract

      A neutral dimeric molecule in crystal form, the diisopropylamido turbo-Grignard reagent "(iPr2N)MgCl⋅LiCl" (see structure; blue N, red O, green Mg, yellow Cl, black C) separates into several charged ate species in dynamic exchange with each other in THF solution as determined by a combination of EXSY and DOSY NMR studies.

      Author(s):Armstrong, David R., Garcia-Álvarez, Pablo, Kennedy, Alan R. ORCID logoORCID: https://orcid.org/0000-0003-3652-6015, Mulvey, Robert E. ORCID logoORCID: https://orcid.org/0000-0002-1015-2564 and Parkinson, John A. ORCID logoORCID: https://orcid.org/0000-0003-4270-6135
      Item type:Article
      ID code:27619
      Notes:This is the peer reviewed version of the following article: Armstrong, DR, Garcia-Álvarez, P, Kennedy, AR, Mulvey, RE & Parkinson, JA 2010, 'Diisopropylamide and TMP turbo-grignard reagents: a structural rationale for their contrasting reactivities' Angewandte Chemie International Edition , vol 49, no. 18, pp. 3185–3188, which has been published in final form at https://doi.org/10.1002/anie.201000539. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
      Keywords:amides, grignard reagents, metalation, structure elucidation, DOSY NMR spectroscopy, Chemistry, Chemistry(all)
      Subjects:Science > Chemistry
      Department:Faculty of Science > Pure and Applied Chemistry
      Depositing user: Mrs Gillian Neeson
      Date deposited:04 Oct 2010 15:31
      Last modified:16 Jan 2020 02:56
      Related URLs:
      URI:https://strathprints.strath.ac.uk/id/eprint/27619
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