Cytotoxic diterpenes from scoparia dulcis
Ahsan, M. and Islam, S.N. and Gray, A.I. and Stimson, W.H. (2003) Cytotoxic diterpenes from scoparia dulcis. Journal of Natural Products, 66 (7). pp. 958-961. ISSN 0163-3864
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Abstract
Four new labdane-derived diterpenes, iso-dulcinol (1), 4-epi-scopadulcic acid B (2), dulcidiol (4), and scopanolal (5), together with two known diterpenes, dulcinol/scopadulciol (3) and scopadiol (6), were isolated from the aerial parts of Scoparia dulcis. The structures were determined by extensive NMR studies. The crude extracts as well as the pure diterpenes showed cytotoxicity against a panel of six human stomach cancer cell lines.
| Creators(s): |
Ahsan, M., Islam, S.N., Gray, A.I.  ORCID: https://orcid.org/0000-0002-0030-9804 and Stimson, W.H.;
| Item type: | Article |
|---|---|
| ID code: | 22868 |
| Keywords: | beta-glucuronidase inhibitor, cell-lines, acid-a, triterpenoids, Pharmacy and materia medica, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Complementary and alternative medicine, Analytical Chemistry, Pharmacology |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Depositing user: | Strathprints Administrator |
| Date deposited: | 07 Jul 2010 10:52 |
| Last modified: | 06 Apr 2020 00:35 |
| URI: | https://strathprints.strath.ac.uk/id/eprint/22868 |
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