Cytotoxic diterpenes from scoparia dulcis

Ahsan, M. and Islam, S.N. and Gray, A.I. and Stimson, W.H. (2003) Cytotoxic diterpenes from scoparia dulcis. Journal of Natural Products, 66 (7). pp. 958-961. ISSN 0163-3864 (http://dx.doi.org/10.1021/np020356j)

Abstract

Four new labdane-derived diterpenes, iso-dulcinol (1), 4-epi-scopadulcic acid B (2), dulcidiol (4), and scopanolal (5), together with two known diterpenes, dulcinol/scopadulciol (3) and scopadiol (6), were isolated from the aerial parts of Scoparia dulcis. The structures were determined by extensive NMR studies. The crude extracts as well as the pure diterpenes showed cytotoxicity against a panel of six human stomach cancer cell lines.

ORCID iDs

Gray, A.I. ORCID: https://orcid.org/0000-0002-0030-9804

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• Item metadata

  Item type:	Article
  ID code:	22868
  Dates:	Date Event July 2003 Published
  Subjects:	Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Strathprints Administrator
  Date deposited:	07 Jul 2010 10:52
  Last modified:	11 Nov 2024 09:29
  URI:	https://strathprints.strath.ac.uk/id/eprint/22868