Pharmacological remodelling of human atrial k+ currents by chronic beta-blockade

Marshall, G. and Rankin, A.C. and Kane, K.A. and Workman, A.J. (2006) Pharmacological remodelling of human atrial k+ currents by chronic beta-blockade. European Heart Journal, 27 (Supple). p. 30. 389. (https://doi.org/10.1093/eurheartj/ehl212)

Abstract

The chronic treatment of patients with a beta-blocker is associated with prolongation of the atrial action potential duration (APD), potentially contributing to its ability to prevent atrial fibrillation (AF). This may involve pharmacological remodelling of atrial K+ currents which affect APD. This project aimed to test the hypothesis that various characteristics of human atrial K+ currents, including voltage, time and rate dependency, differ between patients treated and not treated with a beta-blocker.

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• Item metadata

  Item type:	Article
  ID code:	21247
  Dates:	Date Event August 2006 Published
  Notes:	AHR: Has abstract also been published in 'Heart' (2006), 92, A101-A101?
  Subjects:	Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Strathprints Administrator
  Date deposited:	02 Aug 2011 10:23
  Last modified:	11 Nov 2024 09:30
  URI:	https://strathprints.strath.ac.uk/id/eprint/21247