The interplay between human b cells, eosinophils and helminths: a novel aspect of the hygiene hypothesis
Mammen, A. and Farraye, F.A. and Liang, Y. and Harnett, W. and Shin, H. and Harnett, M.M. and Nikolajczyk, B. and Ganley-Leal, L. (2008) The interplay between human b cells, eosinophils and helminths: a novel aspect of the hygiene hypothesis. American Journal of Tropical Medicine and Hygiene, 79 (6). pp. 337-338. ISSN 0002-9637
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The hygiene hypothesis is based on the premise that lack of exposure to helminths predisposes certain individuals to immune-mediated disease, such as inflammatory bowel disease (IBD). This hypothesis is supported by epidemiological data that shows developed countries with a low prevalence of helminth infections have higher incidence of allergic and inflammatory diseases. Helminths modulate the host immune response in a manner that dampens the exaggerated response to innocuous antigens, such as commensal bacteria.
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Item type: Article ID code: 19349 Dates: DateEventDecember 2008PublishedSubjects: Science > Microbiology > Immunology Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Depositing user: Strathprints Administrator Date deposited: 02 Jun 2010 09:13 Last modified: 08 Apr 2024 17:43 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/19349